Overview
What is an organ transplant?
An organ transplant replaces a failing organ with a healthy
organ. A doctor will remove an organ from another person and place it in your
body. This may be done when your organ has stopped working or stopped working
well because of disease or injury.
Not all organs can be
transplanted. Organs most often transplanted include:
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The kidney
, because of
diabetes,
polycystic kidney disease,
lupus, or other problems.
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The liver
, because of
cirrhosis, which has many causes.
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The heart
, because of
coronary artery disease,
cardiomyopathy,
heart failure, and other heart
problems.
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The pancreas
, because of
diabetes.
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The lung
, because of
cystic fibrosis,
COPD, and other problems.
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The small intestine, because of short bowel syndrome caused by necrotizing enterocolitis, Crohn's disease, and other problems. An intestine transplant is sometimes an option if you have problems with total parenteral nutrition (TPN).
More than one organ can be transplanted at one time. For
example, a heart and lung transplant is possible.
Not everyone is
a good candidate for an organ transplant. Your doctor or a transplant center
will do tests to see if you are. You probably are not a good candidate if you
have an infection, heart disease that is not under control, a
drug or alcohol problem, or another serious health
problem.
If your tests show you are a good candidate, you are put
on a waiting list. It may be days, months, or years before a transplant takes
place.
How successful is an organ transplant?
Organ transplants have been done in the United States since the
1950s. The procedure is always improving, and transplants are more successful
today than ever before. Organ transplant success depends on:
- Which organ is transplanted.
- How
many organs are transplanted. For example, you could have a heart transplant or
a heart and lung transplant.
- The disease that has caused your
organ to fail.
How do you prepare for an organ transplant?
First,
you'll need to have blood and tissue tests done that will be used to match you
with a donor. This is because your immune system may see the new organ as
foreign and reject it. The more matches you have with the donor, the more
likely your body will accept the donor organ.
You'll need to take
care of your health. Continue to take your medicines as prescribed and get
regular blood tests. Follow your doctor’s directions for eating and exercising.
You also may want to talk with a
psychiatrist,
psychologist, or
licensed mental health counselor about your
transplant.
To learn more about what happens, talk to someone who
has had a transplant. Your transplant center or doctor can give you the name of
someone who is willing to share his or her experience with you.
You
may have to wait days, months, or years for your transplant. Be patient, and
ask your doctor what you can do while you're waiting.
What can you expect afterward?
After a transplant,
many people say they feel better than they have in years. What you can and
can't do will depend on the type of transplant you had, other health problems
you have, and how your body reacts to the new organ.
You will have
to take daily antirejection medicines for the rest of your life to prevent your
immune system from rejecting the new organ. You will need less of these
medicines as time goes by.
Because these antirejection medicines
weaken the immune system, you may have to stay away from large crowds for a while and
stay away from people who have infections. Be sure you talk to your doctor before you take any
nonprescription medicines, such as cold remedies. These medicines may cause
problems with your antirejection medicines.
You will also have
regular checkups and blood tests to see how well your new organ is
working.
Depression is common after an organ transplant. If you
think you may be depressed, get help. The earlier depression is treated, the
more quickly you will feel better.
You may need to make some
lifestyle changes to keep your new organ healthy and strong. This can include
eating healthy foods, getting regular exercise, and getting enough sleep. Your
doctor can help you plan any needed changes. Keeping in touch with your
transplant coordinator and your local primary doctor, taking your medicines,
going to your doctor appointments, and making lifestyle changes are all
important.
Who can be an organ donor?
Most people can be
organ donors. If you are interested in donating an organ, contact the United
Network for Organ Sharing (UNOS) at 1-888-894-6361 or go online at www.unos.org
to get more information and to locate the nearest transplant center.
Many people choose to donate an organ upon their death. But a
person can donate certain organs while he or she is still living. These people
are called "living donors." To be a living donor, you must be in good health
and be physically fit, free from long-term diseases such as diabetes or high
blood pressure, free from mental health problems, and between the ages of 18
and 60.
Frequently Asked Questions
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Learning about organ transplant:
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Getting ready:
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After a transplant:
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Living with an organ transplant:
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End-of-life issues:
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Preparing for a Transplant
What causes an organ to stop working?
Organ transplantation
is a more common medical procedure today than in the
past. People are living longer, which means that disease has a longer time to
damage organs. Many diseases can lead to organ failure, including
diabetes,
cirrhosis,
coronary artery disease,
hepatitis C,
chronic obstructive pulmonary disease (COPD), cystic fibrosis, and Crohn's disease.
If you have been living
with a serious chronic disease that has caused a major organ (such as your
heart, kidneys, liver, pancreas, lungs, or intestine) to fail, you may want to ask your
doctor whether an organ transplant is an option for you. Decisions about
whether you will need a transplant are usually made in consultation with a
specialist.
How do I get on the waiting list?
After it is
determined that you need an organ transplant, the next step is getting on the
organ transplant waiting list:
- Obtain a referral from your
doctor.
- Call the transplant center where you choose to have your
transplant. To locate a transplant center near you, ask your doctor or contact the United Network for Organ Sharing by going online at
www.unos.org or calling 1-888-894-6361.
- Schedule an appointment for
an evaluation at the transplant center to find out if you are a good candidate
for transplant. Your transplant center can perform all of the required tests,
or your doctor can order the tests and send the results to the center.
During your evaluation, it is important to learn as much
as you can about the transplant center. You may want to find out whether the
center will accept your insurance, what your options are if you
don't have insurance, and whether support groups are available. Be ready to ask
a lot of questions to make sure the transplant center is a good fit for
you.
The transplant center will notify you within 2 weeks of your
evaluation to let you know whether you have been placed on the waiting list. If
you have questions about your list status, contact the transplant center where
you were evaluated.
It may be days, months, or even years before
you receive a new organ. Waiting may be the hardest part of your transplant.
Your transplant team will consider whether the donor is a good match for you,
the status of your current health, and how long you've been on the waiting list. Your team will also consider the location of the donated organ, because it must be transplanted quickly
to remain in working order.
What if I am not a good candidate for organ transplant?
If you are told that you are not a good candidate for organ transplant,
find out if there are other treatments for your condition. Many people can live
for years with serious health conditions. If transplantation is not an option,
the goal of your care may shift to maintaining your comfort. Talk to your loved
ones about the type of care you would like to receive. Discuss their
expectations as well as your wishes, care needs, finances, and the needs of
your family. Your choices may change as your illness changes.
What do I need to know before having an organ transplant?
It is natural for your
immune system to destroy invading foreign substances
in order to fight off infection and disease. Basically, an organ transplant
from someone else is foreign to your body. When a new organ is placed into your
body, your immune system sees it as foreign and tries to destroy it. The most
important weapons to fight this
rejection are antirejection medicines that prevent
your immune system from attacking the donor organ.
Not everyone is
a good candidate for an organ transplant. You probably are not a good candidate
if you have an active infection, unstable heart disease, or another serious
medical problem. Also, you will not be considered for organ transplant if you
have an active
substance abuse problem. Ask your doctor for more
information about organ transplantation and whether you would be considered a
good candidate.
While transplantation can be a long and
challenging process, your quality of life may be greatly improved.
Because receiving a donor organ is a big responsibility, you'll have to
be committed to taking good care of yourself in order to be approved for a
donor organ. The best way to do this is to take medicines as prescribed, get
regular blood tests, and make any necessary lifestyle changes to stay healthy.
Because there are many emotional issues that may come with a transplant, you
may find it helpful to see a
psychiatrist,
psychologist, or a
licensed mental health counselor about your
transplant.
Success rates usually state how many people who receive
the transplant are living 5 years after the transplant.1
- Kidney:
About 8 or 9 people out of 10 (80% to 90%)
- Liver: About 7 or 8
people out of 10 (74% to 76%)
- Lung: About 5 people out of 10 (53%)
- Pancreas: About 8 or 9 people out of 10 (84% to 88%)
- Heart: About 7 people out of 10 (74%)
- Intestine: About 5 people out of 10 (54%)
How can my loved ones prepare?
There are many ways
your loved ones can provide you with support during and after your organ
transplant. It may be helpful to have at least one support person stay at the
transplant center with you during and after your surgery. Before your
transplant, this person can talk with the transplant coordinator to arrange for
lodging while you are in the hospital. He or she should have a suitcase packed
and be prepared to go to the transplant center with you when you get the call
that your organ is available.
The transplant coordinator can also
tell the support person where to wait during your surgery. Your support person
can be responsible for writing down and asking the transplant team questions
during and after your surgery. Also, he or she can stay with you after the
surgery and watch for any rejection symptoms or unusual behaviors (such as
being overly agitated) that sometimes occur after a transplant.
The support person should know what counseling services are available at
the transplant center and know when to ask for help from an outside resource,
such as another family member, community resources, or your place of
worship.
What tests will I need before my transplant?
Before you can be considered for an organ transplant, you will need to
have medical tests to find out whether you are a good transplant candidate and
to find out your tissue type. Knowing your tissue type will make matching with a donor organ easier. Some tests are required for all organ transplant
candidates, while others are needed to monitor your chronic disease or the
cause of your organ failure. In general, tests that are done for all organ
transplant candidates include:
- A crossmatch for transplant. This is a blood
test that shows whether your body will reject the donor organ immediately.
Antibodies are proteins made by your immune system
that attack and destroy foreign substances (antigens), such
as bacteria and viruses. The crossmatch will mix a donor's blood with your
blood to see whether your antibodies attack the antigens of the donor. If they
do, you are not a good match with the donor.
-
Antibody screen. A panel-reactive antibody (PRA) test measures whether you have
antibodies against a broad range of people. And if you do, it means you are at
higher risk of having rejection, even if the crossmatch shows that you and the
donor are a good match.
-
Blood type.
This is a blood test that shows which type of blood you have—type A, B, O,
or AB. Your
blood type should be compatible with the organ donor's
blood type, although it is sometimes possible to transplant an organ from a
donor with a different blood type.
-
Tissue type.
This is a blood test that shows the genetic makeup of your body's cells.
Each of us has genetic markers on the surface of our white blood cells. We
inherit three different kinds of markers from our mothers and three from our
fathers. The more of these six markers you share with the organ donor, the more
likely it is that your body will accept the donor organ.
- A
mental health assessment. Because many emotional
issues are involved in having an organ transplant, you will be required to take
a mental health assessment to identify any psychological issues that may
prevent you from receiving and properly caring for your new organ. A living
donor is also required to have a mental health assessment before donating an
organ.
The results of these medical tests will be used to match
you with an organ donor. The more matches you have, the more likely your body
will accept the new organ.
What other factors increase my chance for a successful organ transplant?
Other factors that affect your chance of having a
successful organ transplant include:
- The age of the donor organ. In general, the
younger the organ donor, the healthier the tissue. But recent research is
challenging this thought. It may be that some older organs work just as well as
younger organs.
- The length of time that the donor organ is out of
the donor's body. The more quickly an organ is transplanted after it is removed
from the donor, the more viable the organ tissue remains. Your team will make
every effort to quickly transfer the donor organ.
- How well the
organ was preserved just before transplantation. The donor organ must be
properly preserved while it is being transferred, especially if it was
transferred from a long distance. Your team will make every effort to make sure
the donor organ is properly transferred to your location.
What else should I consider?
You may be worried
about having an organ transplant, being in a transplant center or hospital, or
being around medical equipment or doctors. You may have concerns that you will
not survive the surgery. All are normal concerns. Most people who have
had an organ transplant say that it was a good decision and that the surgery
and lifelong use of medicines and lifestyle changes are worth it.
The quality of your life can greatly improve. You should have more energy
soon after your transplant. You may enjoy physical activities or foods that you
haven't been able to enjoy in a long time. After having a transplant, you may
feel better than you have in years—many people report feeling better
immediately after their transplant, even while recovering from the
surgery.
It is always wise to have an
advance directive on file with the transplant center
or hospital where you will receive care. An advance directive provides
instructions about your medical choices should you be unable to make those
choices for yourself. It is a good idea to appoint a
health care agent to make your health decisions if you
are unable to communicate your wishes. For more information, see the topics
Writing an Advance Directive and
Choosing a Health Care Agent.
It is true
that there is a risk of not surviving an organ transplant just as there is with
any surgery. There is also a slight risk that your transplanted organ will not
function immediately. Some people with kidney transplants from deceased donors
require dialysis for a week or more before the kidney functions adequately.
Only a few transplanted organs never function. If the donated organ does not
work well after your transplant or if it stops working over the years, it may
be possible for you to have another organ transplant.
Making the
decision to have an organ transplant can be hard. Talking with someone who
has had an organ transplant may assure you that you can make the lifestyle
changes necessary for a long-lasting, successful transplant.
At the Hospital
How can I prepare for my transplant?
While you are
waiting for your
organ transplant, you will be given a pager or
cell phone so the transplant center can contact you at any time to tell you an
organ is available. Always keep your pager with you. You may also wish to give
the transplant center several numbers where you can be reached and the name and
number of a few people who will always know how to reach you.
Arrange for someone to go with you to the transplant center when you have
the organ transplant. This person can support you, listen to your doctor, and
can help you remember important instructions from your doctor. This person can
also report any change in behaviors or symptoms that you may have either before
or shortly after the transplant. It is helpful to have someone who can be there
to check in on you during your stay in the hospital and during your recovery at
home.
Have your suitcase packed with the things you need to take
with you to the transplant center. Your support person should also have a bag
packed and ready to go at a moment's notice. You never know when you will
receive the call that your organ is available.
What will happen at the hospital?
If you are
called to the hospital or transplant center because a donor organ has been
found, you will immediately be prepared for surgery while final tests are done
to make sure the donor organ is a good match. If it is, you will have
transplant surgery right away. If the organ is not a good match, the organ will
be given to a person who is a better match, and you will be released to go home
and continue to wait for your new organ.
If your current health
condition requires that you be hospitalized while you wait for a donor organ,
you will receive supportive and lifesaving care (such as blood pressure support
for
heart failure) until you are matched with a donor
organ. During that time, you may be given high doses of a
corticosteroid medicine, usually methylprednisolone,
to prepare you for the surgery and prevent rejection. High doses of
corticosteroids may cause side effects such as
high blood pressure,
high cholesterol, weight gain, sleep problems, and
anxiety. Corticosteroids can also cause more severe
side effects such as extreme agitation, paranoia, and
psychosis (trouble telling the difference between what
is real and what is not real)—some people may feel "out of it" or have
hallucinations while taking high doses of steroids.
But these side effects are temporary and will go away after you stop taking the
corticosteroid medicine.
How long will I be hospitalized after the transplant?
Your recovery time after an organ transplant depends on how healthy you
are prior to surgery, which organ was transplanted, and whether your body
accepts the donated organ. A longer hospital stay may be needed for a heart or
lung transplant than for a kidney transplant. Some people are out of the
hospital within a few days after their transplant, while others may need to
stay for a few weeks.
After the Transplant
Why does organ rejection occur?
Your body has a
natural defense system called the
immune system that protects you from infection and
disease. The immune system defends your body by producing
antibodies and "killer" cells that destroy foreign
substances (such as viruses and bacteria). Since the donor organ doesn't match
your own tissue exactly, your body tries to destroy the transplanted organ by
rejecting it. Rejection is nature's way of protecting
your body.
What medicines will I need to take?
After an organ
transplant, you will need to take antirejection medicines, or
immunosuppressants, for as long as you have the donor organ. Because your
immune system will try to destroy the new organ, antirejection medicines are
needed to decrease your immune system's response so the new organ stays
healthy.
Antirejection medicines weaken your immune system and
decrease your body's ability to fight infections, cancer, and other diseases.
Over the years since organ transplants were first done, these medicines have
greatly improved. Researchers are finding out more all the time about how to
better regulate the immune system after a transplant. Current medicines still
have the potential to speed up illness or create new disease, such as heart
problems,
diabetes, cancer, and
osteoporosis. But these medicines also will save your
life by keeping your body from rejecting the donor organ. It is important to
take these medicines daily and exactly as prescribed.
Taking
medicines daily for the rest of your life is not as hard as it sounds. It may
help to talk to someone who has had a transplant and who can give you some
assurance that you will be able to make the medicines a part of your daily
routine. Over time, probably, fewer medicines will be needed. Additional
medicines may be needed now and then to fight infection or other health
problems related to your transplant.
In general, the antirejection
medicines you will take after an organ transplant include:
Corticosteroids, such as prednisone or methylprednisolone. A
high dose of corticosteroid, often methylprednisolone, is given right before
your transplant, to decrease your immune system's activity, reduce
inflammation, and prevent rejection. High doses of
corticosteroids are usually continued for a few days after your surgery and
then tapered to the lowest dose that helps prevent rejection. Taking high doses
of corticosteroids for just a few days may cause temporary side effects such as
high blood pressure, high cholesterol, weight gain, sleep problems, and
anxiety. High doses can sometimes cause more severe side effects, such as
extreme agitation, paranoia, and
psychosis (trouble telling the difference between what
is real and what is not real)—some people may feel "out of it" or have
hallucinations while taking high doses of steroids.
But these side effects are temporary. Prolonged use of corticosteroids can
cause
glaucoma, steroid-induced
diabetes, and increase your risk of getting an
opportunistic infection (such as pneumocystis
pneumonia), which is a type of infection that occurs in people with
weakened immune systems. Some experts are finding that
some people may be able to avoid use of steroids or to use them
sparingly.
Calcineurin inhibitors, such as
tacrolimus and cyclosporine. These block the message that causes rejection. You
probably will always need to take calcineurin inhibitors, because they are an
important part of your lifelong care after a transplant. These medicines
are helpful, but they also have potentially serious side effects such as high blood
pressure, too much potassium in the blood (hyperkalemia), and kidney problems.
These medicines can also cause nausea, vomiting, diarrhea, high cholesterol,
tremors, and
seizures. And they can put you at increased risk for infection and cancer. There is a great deal of research on the development of
newer calcineurin inhibitors with fewer side effects. Ask your doctor for more
information if you are having any of these side effects.
Antiproliferative agents, such as mycophenolate mofetil,
azathioprine, and sirolimus. Antiproliferative agents prevent the immune cells
from multiplying. These antirejection medicines are also an important part of
your lifelong care after a transplant. They prevent your immune system from
attacking and destroying the donor organ. Common side effects can include
nausea, anemia, reduced number of white blood cells (leukopenia), high
triglycerides, and intestinal upset. Antiproliferative agents also increase
your risk of getting an opportunistic infection, cancer, and other
life-threatening conditions.
Monoclonal antibodies, such as daclizumab, basiliximab, and rituximab. These antibodies block the growth of immune cells that are responsible for rejection. They are used early after transplantation with
calcineurin inhibitors and antiproliferative agents.
Polyclonal antibodies, such as antithymocyte globulin-equine
and antithymocyte globulin-rabbit. Polyclonal antibodies temporarily deplete
the body's immune cells. These medicines are used in the hours and days
immediately after your organ transplant to prevent your body from rejecting the
donor organ. They may also be used again if your body starts to reject the
donor organ. They are often used to reduce early use of calcineurin inhibitors,
which can have serious side effects. Side effects of polyclonal antibodies
include fever, itching, joint pain, and decreased number of white blood cells
(leukopenia). Severe side effects may include an increased risk for cancer and
opportunistic infections, serum sickness (a bad reaction to your own tissues),
and a condition that prevents your body from making antibodies that fight
infection.
You may have to take other medicines to prevent infection or to control other health problems you have (like high blood pressure).
What kind of physical issues will I face after transplant?
Almost immediately after a transplant, many people
report feeling better than they have in years. The physical limitations you
have will depend on the type of transplant you had, other conditions you may
have, and whether your body rejects the donor organ. You will likely not face
major physical limitations after you have healed from your transplant.
The daily antirejection medicines can cause some bothersome and sometimes
serious side effects in some people.
High blood pressure and
high cholesterol are common problems after a
transplant, although they can be treated with other medicines. You
may be at increased risk for getting certain types of cancer and conditions
such as diabetes. You will be at higher risk for infections, especially
opportunistic infections, because your antirejection medicines will weaken your
immune system. Be sure to keep your regular appointments with your
doctor or the transplant center so you can be monitored for these
illnesses.
What kind of emotional issues will I face?
Having
an organ transplant may cause many emotional issues both for you and those who
care about you. When your organ comes from a deceased donor, you may sometimes
think about that and what it meant to the donor's family. It is common to have
some
depression after an organ transplant, although not
everyone does. If you think you may be depressed, it is important to tell your
transplant coordinator, doctor, or someone who cares about you. The earlier
depression is treated, the more quickly you will recover and the better you
will feel.
Staying Healthy
You can keep your new organ healthy
and prolong your life after an
organ transplant by:
- Keeping your doctor appointments. Regular
contact with your doctor means new illnesses such as infections or other
possibly life-threatening problems may be detected and treated early. Also,
regular follow-up with your doctor is important for monitoring rejection, a
concern that never goes away. Your doctor will also check you closely for
medicine side effects.
- Getting regular blood and tissue tests.
This is the only way that your doctor will be able to tell if your body is
rejecting the new organ, if you are having serious side effects from the
medicines, or if you are getting a new illness. Remember that just because you
develop rejection does not mean that you will lose the new organ. If it is
caught early, you may be given additional or different medicines to prevent
rejection. But in order to catch the rejection or new illness early, you must
have regular blood monitoring.
- Taking your medicines exactly as
prescribed. Medicines after a transplant are critical to your health. Talk with
your doctor to make sure you understand what to do if you miss a dose. For some
people, it helps to organize daily medicines by placing the pills in containers
marked with the days of the week. Other people find it easier to set an alarm
for the times they need to take medicines. When you make your own plan for
taking your daily medicines, it will be easy to remember.
- Telling
your doctor immediately if you have an adverse reaction to a
medicine.
- Not taking any nonprescription medicines, such as cold
remedies, before talking with your doctor. These medicines may interact poorly
with your antirejection medicines. Also, do not take any
herbal remedies without first talking about it with
your doctor.
Lifestyle activities that you can do to keep healthy and
prolong the life of your new organ may include:
- Getting regular exercise. It is important to
keep your muscles strong or it will become harder for you to walk, dress, or do
other daily activities. Staying in shape and not gaining weight will help keep
your body and new organ healthy. Many diseases (such as diabetes) are
associated with being overweight, and some of the medicines may put you at a
higher risk for getting these diseases. Gentle exercise such as
walking,
water aerobics, and
yoga can help you stay in shape and can also help
reduce stress. For more information, see:
Fitness: Walking for wellness.
- Eating regular, healthy meals. Healthy eating can
control your weight, blood pressure, cholesterol, and blood sugar levels.
Eating a balanced diet will give you energy and help your body fight disease
and illness. Your doctor may suggest that you eliminate or reduce salt and
high-fat foods from your diet. Be sure to get plenty of calcium and
vitamin D because a side effect of corticosteroids is
osteoporosis, or thinning bones. For more information,
see the topic
Healthy Eating.
- Paying attention to your
body so you can detect new illness. Knowing how you normally feel, how much
energy you have, and how active you are can help you quickly identify new
problems as they arise, because you will notice a change in your energy
level.
- Telling your dentist that you have had an organ transplant.
Special precautions may be needed in teeth cleaning or other dental work. It is
always important to keep your gums and teeth clean and healthy, but it is
especially true after a transplant. The antirejection medicines may increase
your risk of mouth infections.
- Staying away from people who are
sick. Your immune system is weakened by the antirejection drugs. It is
important that you stay healthy. Before you do any traveling, talk with your
doctor to see if you need to take any precautionary
measures.
- Carrying a medical identification card or wearing a
medical ID bracelet or necklace that states that you have had an organ transplant.
This information helps emergency personnel in the event you are unconscious,
severely injured, or unable to answer questions.
What kind of emotional issues will I face?
Having
an organ transplant may cause many emotional issues both for you and those who
care about you. If your organ came from a deceased donor, you may sometimes
think about that and what it meant to the donor's family. It is common to have
some
depression after an organ transplant, although not
everyone does. If you think you may be depressed, be sure to tell your
transplant coordinator, doctor, or someone who cares about you. The earlier
depression is treated, the more quickly you will recover and the better you
will feel.
Why should I keep in contact with the transplant center?
You will likely have a primary care doctor or specialist to provide
for your regular health care after your transplant. Also, your
transplant coordinator is a very helpful resource for questions you may
have about medicines or what to expect in the months and years after your
transplant or if new health issues arise.
Donor Information
Donor organs are in demand—there are currently more than 100,000
people on the national
organ transplant waiting list. If you are interested
in donating an organ, contact the United Network for Organ Sharing (UNOS) at
1-888-894-6361 or go online at www.unos.org to get more information and to
locate the nearest transplant center.
Many people choose to donate
their organs upon their death. If you decide to be an organ donor upon your death, make sure your family, friends, and doctor know about your wishes. You may want to fill out a donor card. Or you can prepare a living will or advance care directive that describes your wishes to be an organ donor.
People can also donate some organs (such as a kidney
or portion of liver) while they are still living. These people are called
"living donors."
Although controversial, Internet donor-matching services
have appeared in recent years to help people who need an organ transplant
to contact potential living donors. Some experts believe these services undermine
the current system, which is based on donated organs going to people who are
most in need and those waiting the longest for a donor. Others believe online
donor matching services provide a useful resource for helping people who have
had problems finding a donor within the current system. For more information
about these services, talk to your doctor.
Two types of surgery
are commonly used to remove an organ or a portion of an organ from a living
donor.
- Open surgery involves cutting the skin,
muscles, and tissues to remove the organ. When open surgery is done, the person
may have more pain and a longer recovery time.
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Laparoscopic surgery
is a procedure in which a surgeon
makes a number of small incisions and uses scopes to remove a kidney from a
living donor.
You do not have to be a blood relative (such as a sibling
or parent) of a living donor to receive a donor organ. A living donor can be
someone who is emotionally related to you such as a close friend or spouse, or
the donor can even be a stranger. In order to become a living donor, the person
must be in good health, physically fit, free from chronic diseases such as
diabetes or high blood pressure, free from psychiatric conditions, and between
the ages of 18 to 60. Race and gender are not important considerations for
becoming a living donor.
Other Places To Get Help
Organizations
|
American Society of Transplantation
|
| 15000 Commerce Parkway |
| Suite C |
| Mt. Laurel, NJ 08054 |
| Phone: |
(856) 439-9986 |
| Fax: |
(856) 439-9982 |
| E-mail: |
ast@ahint.com |
| Web Address: |
www.healthytransplant.com |
| |
|
Healthy Transplant is a Web site sponsored by the American Society of Transplantation. This Web site was created to help people learn about transplantation. Patients can build a profile and take an active role in their health care. The Web site was created to help patients and family members understand more about transplantation and help people be more involved in their health care.
|
|
|
Donate Life America
|
| 700 North Fourth Street |
| Richmond, VA 23219 |
| Phone: |
804-782-4920 |
| Fax: |
804-782-4643 |
| Web Address: |
http://donatelife.net |
| |
|
Donate Life America is an organization supported by the transplant community. This group works at a local level to educate Americans on the need for organ donation. The Web site includes information on how to become an organ donor, other information on organ donation, and personal stories about organ donors and recipients. This group used to be called the Coalition on Donation.
|
|
|
OrganDonor.Gov
|
| Health Resources and Services Administration, U.S. Department of Health and Human Services |
| 200 Independence Avenue SW |
| Washington, D.C. 20201 |
| Phone: |
1-877-696-6775
toll-free
(202) 619-0257
|
| Web Address: |
www.organdonor.gov |
| |
|
The U.S. Department of Health and Human Services provides information on organ tissue donation and transplantation through its OrganDonor.gov Web site. It lists the number of people currently on the waiting list for transplants. It gives information on how to become an organ or tissue donor and describes the process of transplantation. It also provides information on research and guidelines, and it lists resources such as locations of transplant centers.
|
|
|
United Network for Organ Sharing
(UNOS)
|
| 700 North 4th Street |
| Richmond, VA 23219 |
| Phone: |
1-888-894-6361 |
| Web Address: |
www.unos.org |
| |
|
The United Network for Organ Sharing (UNOS) is a
nonprofit scientific and educational organization that administers the nation's
only Organ Procurement and Transplantation Network (OPTN). It was established
by the U.S. Congress in 1984. UNOS collects and manages data about every
transplant event occurring in the United States, facilitates the organ matching
and placement process, and brings together health professionals, transplant
recipients, and donor families to develop organ transplantation policy.
UNOS:
- Matches donors to recipients and coordinates
the organ-sharing process 24 hours a day, 365 days a
year.
- Maintains the databases that contain all clinical transplant
data for every transplant event that occurs in the United
States.
- Performs data analyses, fills data requests, produces the
Annual and other data reports, and authors authoritative
publications.
- Monitors every organ match to ensure adherence to
UNOS policy, and works with the Board of Directors to develop equitable
policies that maximize the limited supply of organs.
- Offers support
to members of the transplant community. These services include seminar
planning, providing educational programs and workshops, and much more.
- Provides assistance to patients, family members, and friends, and
sets professional standards for efficiency and quality patient
care.
- Raises public awareness about the importance of organ
donation.
- Works to keep patients informed about transplant issues
and policies.
- Offers comprehensive travel and event planning to
assist organizations within the transplant community.
|
|
References
Citations
-
Health Resources and Services Administration (2007).
2007 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1997–2006. Available online:
http://www.ustransplant.org/annual_reports/current.
Other Works Consulted
- Carithers RL, Perkins JD (2007). Liver and pancreas
transplantation. In DC Dale, DD Federman, eds., ACP Medicine, section 4, chap. 15. New York: WebMD.
- Klassen DK, Weir MR (2007). Renal transplantation. In
DC Dale, DD Federman, eds., ACP Medicine, section 10,
chap. 11. New York: WebMD.
- Punch JD (2010). Organ transplantation. In GM Doherty ed., Current Diagnosis and Treatment Surgery, 13th ed., pp. 1233–1250. New York: McGraw-Hill.
- Trulock EP (2007). Lung transplantation. In DC Dale,
DD Federman, eds., ACP Medicine, section 14, chap. 17.
New York: WebMD.
- Hodson EM, et al. (2008). Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients. Cochrane Database of Systematic Reviews (2).
- Pham MX, et al. (2008). Surgical treatment of heart
failure, cardiac transplantation, and mechanical ventricular support. In V
Fuster et al., eds., Hurst's The Heart, 12th ed., pp.
761–790. New York: McGraw-Hill.
Credits
|
By
|
Healthwise Staff |
|
Primary Medical Reviewer
|
Anne C. Poinier, MD - Internal Medicine |
|
Specialist Medical Reviewer
|
Philip Belitsky, MD, FRCSC - Urology |
|
Last Revised
|
January 8, 2010 |